UHRF1 Antibody (1A1B1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61838

Novus Biologicals, part of Bio-Techne
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NBP2-61838
NBP2-61838-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 1A1B1

Format

BSA Free

Concentration

1 mg/ml

View all UHRF1 Antibodies »

Product Summary for UHRF1 Antibody (1A1B1) - BSA Free

Immunogen

Purified recombinant fragment of human UHRF1 (AA: 616-755) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

89.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for UHRF1 Antibody (1A1B1) - BSA Free

Western Blot: UHRF1 Antibody (1A1B1)BSA Free [NBP2-61838]

Western Blot: UHRF1 Antibody (1A1B1)BSA Free [NBP2-61838]

Western Blot: UHRF1 Antibody (1A1B1) [NBP2-61838] - Analysis using UHRF1 mAb against HEK293 (1) and UHRF1 (AA: 616-755)-hIgGFc transfected HEK293 (2) cell lysate.
Immunocytochemistry/ Immunofluorescence: UHRF1 Antibody (1A1B1) - BSA Free [NBP2-61838]

Immunocytochemistry/ Immunofluorescence: UHRF1 Antibody (1A1B1) - BSA Free [NBP2-61838]

Immunocytochemistry/Immunofluorescence: UHRF1 Antibody (1A1B1) [NBP2-61838] - Analysis of Hela cells using UHRF1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Immunohistochemistry: UHRF1 Antibody (1A1B1) - BSA Free [NBP2-61838]

Immunohistochemistry: UHRF1 Antibody (1A1B1) - BSA Free [NBP2-61838]

Immunohistochemistry: UHRF1 Antibody (1A1B1) [NBP2-61838] - Analysis of paraffin-embedded esophageal cancer tissues using UHRF1 mouse mAb with DAB staining.
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Applications for UHRF1 Antibody (1A1B1) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Immunohistochemistry

1:200-1:1000

Immunohistochemistry-Paraffin

1:200-1:1000

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UHRF1

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.;

Long Name

E3 ubiquitin-protein ligase UHRF1

Alternate Names

hNp95, hUHRF1, HuNp95, ICBP90, NP95, Nuclear protein 95, RNF106

Gene Symbol

UHRF1

Additional UHRF1 Products

Product Documents for UHRF1 Antibody (1A1B1) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for UHRF1 Antibody (1A1B1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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