ULBP-2 Antibody (MM0593-7F33) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11987B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-11987AF350

Alexa Fluor 405

NBP2-11987AF405

Alexa Fluor 488

NBP2-11987AF488

Alexa Fluor 532

NBP2-11987AF532

Alexa Fluor 594

NBP2-11987AF594

Alexa Fluor 647

NBP2-11987AF647

Alexa Fluor 700

NBP2-11987AF700

Alexa Fluor 750

NBP2-11987AF750

Allophycocyanin

NBP2-11987APC

CoraFluor 1

NBP2-11987CL1

DyLight 350

NBP2-11987UV

DyLight 405

NBP2-11987V

DyLight 488

NBP2-11987G

DyLight 550

NBP2-11987R

DyLight 594

NBP2-11987DL594

DyLight 650

NBP2-11987C

DyLight 680

NBP2-11987FR

DyLight 755

NBP2-11987IR

FITC

NBP2-11987F

HRP

NBP2-11987H

Janelia Fluor 525

NBP2-11987JF525

Janelia Fluor 549

NBP2-11987JF549

Janelia Fluor 585

NBP2-11987JF585

Janelia Fluor 635

NBP2-11987JF635

Janelia Fluor 646

NBP2-11987JF646

Janelia Fluor 669

NBP2-11987JF669

mFluor Violet 450 SE

NBP2-11987MFV450

mFluor Violet 500 SE

NBP2-11987MFV500

mFluor Violet 610 SE

NBP2-11987MFV610

PE

NBP2-11987PE

PerCP

NBP2-11987PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-11987

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, Flow Cytometry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₂ Clone # MM0593-7F33

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ULBP-2 Antibodies »

Product Specifications

Immunogen

Human recombinant ULBP-2

Reactivity Notes

0

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₂

Applications for ULBP-2 Antibody (MM0593-7F33) [Biotin]

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: ULBP-2

Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-2

Alternate Names

ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, ULBP2

Gene Symbol

ULBP2

Additional ULBP-2 Products

Product Documents for ULBP-2 Antibody (MM0593-7F33) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for ULBP-2 Antibody (MM0593-7F33) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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