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UNC13D/Munc 13-4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31072

Novus Biologicals, part of Bio-Techne
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NBP1-31072

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human UNC13D/Munc 13-4. The exact sequence is proprietary.

Localization

Cytoplasm, Membrane, Peripheral membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for UNC13D/Munc 13-4 Antibody

Western Blot: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Western Blot: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Western Blot: UNC13D/Munc 13-4 Antibody [NBP1-31072] - Sample (30 ug of whole cell lysate) A: Jurkat B: K562 5% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Immunocytochemistry/ Immunofluorescence: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Immunocytochemistry/Immunofluorescence: UNC13D/Munc 13-4 Antibody [NBP1-31072] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Immunohistochemistry-Paraffin: UNC13D/Munc 13-4 Antibody [NBP1-31072]

Immunohistochemistry-Paraffin: UNC13D/Munc 13-4 Antibody [NBP1-31072] - Munc 13-4 Antibody [NBP1-31072] - Paraffin-embedded Stomach, using antibody at 1:100 dilution.

Applications for UNC13D/Munc 13-4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UNC13D

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Long Name

UNC-13 Homolog D

Alternate Names

FHL3, HLH3, HPLH3, Munc13-4

Gene Symbol

UNC13D

Additional UNC13D Products

Product Documents for UNC13D/Munc 13-4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for UNC13D/Munc 13-4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.