UPF2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-94094

Novus Biologicals, part of Bio-Techne
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NBP2-94094-0.02ml
NBP2-94094-0.1ml
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all UPF2 Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1272 of human UPF2 (NP_542166.1). GPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for UPF2 Antibody - BSA Free

Western Blot: UPF2 AntibodyBSA Free [NBP2-94094]

Western Blot: UPF2 AntibodyBSA Free [NBP2-94094]

Western Blot: UPF2 Antibody [NBP2-94094] - Analysis of extracts of various cell lines, using UPF2 . Exposure time: 60s.
Immunohistochemistry-Paraffin: UPF2 Antibody - BSA Free [NBP2-94094]

Immunohistochemistry-Paraffin: UPF2 Antibody - BSA Free [NBP2-94094]

Immunohistochemistry-Paraffin: UPF2 Antibody [NBP2-94094] - Paraffin-embedded rat kidney using UPF2 .

Applications for UPF2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50 - 1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: UPF2

UPF2 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.

Alternate Names

DKFZp434D222, hUpf2, KIAA1408MGC138835, Nonsense mRNA reducing factor 2, regulator of nonsense transcripts 2, RENT2MGC138834, smg-3, UPF2 regulator of nonsense transcripts homolog (yeast), Up-frameshift suppressor 2 homolog, yeast Upf2p homolog

Gene Symbol

UPF2

Additional UPF2 Products

Product Documents for UPF2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for UPF2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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