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URI Antibody (PD00-48)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32096

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-32096

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # PD00-48

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic peptide. (Uniprot: O94763)

Localization

Nucleus, Cytoplasm, Mitochondrion, Cell projection.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for URI Antibody (PD00-48)

URI Antibody (PD00-48)

Immunohistochemistry: URI Antibody (PD00-48) [NBP3-32096]

Immunohistochemistry: URI Antibody (PD00-48) [NBP3-32096] - Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue with Rabbit anti-URI antibody (NBP3-32096) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (NBP3-32096) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Applications for URI Antibody (PD00-48)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH7.4), 0.1% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: URI

RMP [RNA polymerase II subunit 5(RPB5)-mediating protein] interacts with RPB5 to negatively regulate RNA polymerase II transcription. RMP has corepressor activity that is facilitated by its association with DMAP1 (DNA methyltransferase 1-associating protein). RMP appears to be involved in mTOR kinase signaling.

Alternate Names

chromosome 19 open reading frame 2, FLJ10575, NNX3RPB5-mediating protein, Protein NNX3, RMPunconventional prefoldin RPB5 interactor, RNA polymerase II subunit 5-mediating protein, URIRNA polymerase II, subunit 5-mediating protein

Gene Symbol

URI1

Additional URI Products

Product Documents for URI Antibody (PD00-48)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for URI Antibody (PD00-48)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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