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USP52 Antibody (6A7)

Novus Biologicals, part of Bio-Techne | Catalog # H00009924-M01

Novus Biologicals, part of Bio-Techne
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H00009924-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 6A7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

USP52 (NP_055686, 1099 a.a. ~ 1198 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Reactivity Notes

Human. Other species not tested.

Localization

Cytoplasmic and Nuclear. Note=Shuttles between nucleus and cytoplasm.

Specificity

USP52 - ubiquitin specific peptidase 52

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for USP52 Antibody (6A7)

Immunocytochemistry/ Immunofluorescence: USP52 Antibody (6A7) [H00009924-M01]

Immunocytochemistry/ Immunofluorescence: USP52 Antibody (6A7) [H00009924-M01]

Immunocytochemistry/Immunofluorescence: USP52 Antibody (6A7) [H00009924-M01] - Analysis of monoclonal antibody to PAN2 on HeLa cell . Antibody concentration 10 ug/ml.

Applications for USP52 Antibody (6A7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: USP52

USP52 shows homology to the ubiquitin specific peptidase family. However, it has no ubiquitin carboxyl terminal hydrolase activity since it lacks a conserved catalytic Cys at position 525. It functions in cytoplasmic mRNA decay as part of the Pan nuclease complex which shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein.

Alternate Names

EC 3.1.13.4, FLJ39360, hPan2, Inactive ubiquitin carboxyl-terminal hydrolase 52, KIAA0710PAB-dependent poly(A)-specific ribonuclease subunit 2, NALP4, PABP-dependent poly(A) nuclease 2, PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae), PAN2 polyA specific ribonuclease subunit, PYPAF4, ubiquitin specific peptidase 52, ubiquitin specific protease 52, USP52

Entrez Gene IDs

9924 (Human)

Gene Symbol

PAN2

Additional USP52 Products

Product Documents for USP52 Antibody (6A7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for USP52 Antibody (6A7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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