V2 Vasopressin R/AVPR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-93162

Novus Biologicals, part of Bio-Techne
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NBP2-93162-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all V2 Vasopressin R/AVPR2 Antibodies »

Product Summary for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 232-371 of human AVPR2 (NP_000045.1). IHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Western Blot: V2 Vasopressin R/AVPR2 AntibodyBSA Free [NBP2-93162]

Western Blot: V2 Vasopressin R/AVPR2 AntibodyBSA Free [NBP2-93162]

Western Blot: V2 Vasopressin R/AVPR2 Antibody [NBP2-93162] - Analysis of extracts of various cell lines, using V2 Vasopressin R/AVPR2 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

Applications for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: V2 Vasopressin R/AVPR2

The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.

Long Name

Arginine Vasopressin Receptor 2

Alternate Names

ADHR, AVPR2, DI1, DIR3, NDI, V2 VasopressinR, V2R

Gene Symbol

AVPR2

Additional V2 Vasopressin R/AVPR2 Products

Product Documents for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for V2 Vasopressin R/AVPR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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