V2 Vasopressin R/AVPR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS272

Novus Biologicals, part of Bio-Techne
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NLS272
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Hamster, Monkey, Rabbit

Cited:

Mouse

Predicted:

Bat (95%), Canine (90%), Chimpanzee (100%), Orangutan (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all V2 Vasopressin R/AVPR2 Antibodies »

Product Specifications

Immunogen

Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human V2 Vasopressin R/AVPR2.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Baboon (95%), Bovine (80%).

Localization

Cell Membrane

Specificity

Human AVPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Colon, carcinoma
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Analysis of anti-AVPR2 antibody with human kidney, renal tubules.
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS272]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS272] - Human Lung, Adenocarcinoma tissue after heat-induced antigen retrieval.
View 3 more images

Applications for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

26 ug/ml
Application Notes
Use in IHC-Frozen reported in scientific literature (PMID: 23399889)..
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: V2 Vasopressin R/AVPR2

The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.

Long Name

Arginine Vasopressin Receptor 2

Alternate Names

ADHR, AVPR2, DI1, DIR3, NDI, V2 VasopressinR, V2R

Entrez Gene IDs

554 (Human)

Gene Symbol

AVPR2

Additional V2 Vasopressin R/AVPR2 Products

Product Documents for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for V2 Vasopressin R/AVPR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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