V2 Vasopressin R/AVPR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS273

Novus Biologicals, part of Bio-Techne
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NLS273
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all V2 Vasopressin R/AVPR2 Antibodies »

Product Specifications

Immunogen

Synthetic 15 amino acid peptide from C-terminus of human V2 Vasopressin R/AVPR2.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (87%), Canine (80%).

Specificity

Human AVPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS273] - Anti-AVPR2 / V2R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS273] - Analysis anti-AVPR2 antibody with kidney, renal tubules at 3 ug/ ml.
Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody - BSA Free [NLS273]

Immunohistochemistry-Paraffin: V2 Vasopressin R/AVPR2 Antibody [NLS273] - Analysis of anti-AVPR2 / V2R antibody with human colon, carcinoma.

Applications for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

3 - 6 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: V2 Vasopressin R/AVPR2

The human AVPR2 locus encodes vasopressin receptor type 2, a member of the vasopressin/oxytocin family subfamily. V2 receptor has been shown to concentrate the urine and maintain water homeostasis by responding to the pituitary hormone arginine vasopressin (AVP). Loss of gene function results in the disease Nephrogenic Diabetes Insipidus (NDI). When extrarenal V2 receptors are stimulated by infusion of a V2 selective agonist (dDAVP), a variety of clotting factors are released into the bloodstream. The physiologic importance of this property is not known; its absence does not appear to be detrimental in NDI patients. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts. The V2 Receptor is also expressed outside the kidney although its tissue localization is uncertain. AVPR2 expression has also been described in brain, breast, fetal lung tissue and lung cancer associated with alternative splicing. ESTs have been isolated from normal lung and pancreatic cancer libraries.

Long Name

Arginine Vasopressin Receptor 2

Alternate Names

ADHR, AVPR2, DI1, DIR3, NDI, V2 VasopressinR, V2R

Entrez Gene IDs

554 (Human)

Gene Symbol

AVPR2

Additional V2 Vasopressin R/AVPR2 Products

Product Documents for V2 Vasopressin R/AVPR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for V2 Vasopressin R/AVPR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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