Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-33566

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # ARC5017-02

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Vang-like Protein 2/VANGL2 Antibodies »

Product Summary for Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

Immunogen

A phospho specific peptide corresponding to residues surrounding S14/S17 of human Vang-like Protein 2/VANGL2

Sequence:
SGHSR

Modification

p Ser 14, p Ser 17

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

Application
Recommended Usage

ELISA

Recommended starting concentration is 1 ug/mL

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Vang-like Protein 2/VANGL2

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Alternate Names

LPP1, LTAP, STB1, STBM, Strabismus, Vang like Protein 2, VANGL2

Gene Symbol

VANGL2

Additional Vang-like Protein 2/VANGL2 Products

Product Documents for Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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