Vang-like Protein 2/VANGL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24704

Novus Biologicals, part of Bio-Techne
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NBP2-24704
NBP2-24704SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine, Canine, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Vang-like Protein 2/VANGL2 Antibodies »

Product Summary for Vang-like Protein 2/VANGL2 Antibody

Immunogen

A portion of amino acids 300-350 of human Van Gogh like-2 protein was used as the immunogen.

Reactivity Notes

Chimpanzee (100%), Opossum, Equine (93%), Chicken, Xenopus (73%).

Specificity

100% homologous in human isoform CRA_a, CRA_b and CRA_c).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vang-like Protein 2/VANGL2 Antibody

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704]

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704]

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704] - Analysis of Van Gogh like-2 in human brain lysate in the 1) absence and2) presence of immunizing peptide, 3) mouse brain and 4) rat brain using this antibody. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704]

Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704]

Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP2-24704] - Analysis of Van Gogh like-2 in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

Applications for Vang-like Protein 2/VANGL2 Antibody

Application
Recommended Usage

Western Blot

4-6 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Vang-like Protein 2/VANGL2

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Alternate Names

LPP1, LTAP, STB1, STBM, Strabismus, Vang like Protein 2, VANGL2

Gene Symbol

VANGL2

Additional Vang-like Protein 2/VANGL2 Products

Product Documents for Vang-like Protein 2/VANGL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vang-like Protein 2/VANGL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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