Vanin-1/VNN1 Antibody (2B10)

Novus Biologicals, part of Bio-Techne | Catalog # H00008876-M05

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2B10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Vanin-1/VNN1 Antibodies »

Product Specifications

Immunogen

VNN1 (NP_004657, 298 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KLLLSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQI

Specificity

vanin 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Vanin-1/VNN1 Antibody (2B10)

ELISA: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05]

ELISA: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05]

ELISA: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05] - Detection limit for recombinant GST tagged VNN1 is approximately 0.1ng/ml as a capture antibody.
Immunoprecipitation: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05]

Immunoprecipitation: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05]

Immunoprecipitation: Vanin-1/VNN1 Antibody (2B10) [H00008876-M05] - Analysis of VNN1 transfected lysate using anti-VNN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with VNN1 rabbit polyclonal antibody.

Applications for Vanin-1/VNN1 Antibody (2B10)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against recombinant protein on ELISA. GST alone used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Vanin-1/VNN1

This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24.

Alternate Names

HDLCQ8, Pantetheinase, Pantetheine hydrolase, Tiff66, Vanin1, VNN1

Entrez Gene IDs

8876 (Human)

Gene Symbol

VNN1

OMIM

603570 (Human)

UniProt

NP_004657 (Human)

Additional Vanin-1/VNN1 Products

Product Documents for Vanin-1/VNN1 Antibody (2B10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vanin-1/VNN1 Antibody (2B10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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