Vanin-1/VNN1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25222

Novus Biologicals, part of Bio-Techne
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NBP3-25222
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Vanin-1/VNN1 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Vanin-1/VNN1 using the following amino acid sequence: VFPEVLLSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLYEKDWASNASSGLTAQARIIMLIVIAPIVCSLSW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vanin-1/VNN1 Antibody

Vanin-1/VNN1 Antibody Immunocytochemistry/Immunofluorescence: Vanin-1/VNN1 Antibody [NBP3-25222]

Immunocytochemistry/Immunofluorescence: Vanin-1/VNN1 Antibody [NBP3-25222]

Staining of human cell line EFO-21 shows localization to vesicles.

Applications for Vanin-1/VNN1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Vanin-1/VNN1

VNN1 encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq]

Alternate Names

HDLCQ8, Pantetheinase, Pantetheine hydrolase, Tiff66, Vanin1, VNN1

Gene Symbol

VNN1

Additional Vanin-1/VNN1 Products

Product Documents for Vanin-1/VNN1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Vanin-1/VNN1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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