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VE-Statin/EGFL7 Antibody (2H6)

Novus Biologicals, part of Bio-Techne | Catalog # H00051162-M01

Novus Biologicals, part of Bio-Techne
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H00051162-M01

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 2H6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

EGFL7 (AAH12377.1, 24 a.a. ~ 273 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. YRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDERSARRGGCPQRCINTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLLVHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS

Reactivity Notes

Human. Other species not tested.

Localization

Secreted

Specificity

EGFL7 - EGF-like-domain, multiple 7

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for VE-Statin/EGFL7 Antibody (2H6)

Sandwich ELISA: VE-Statin/EGFL7 Antibody (2H6) [H00051162-M01] - Detection limit for recombinant GST tagged EGFL7 is approximately 0.03ng/ml as a capture antibody.

Applications for VE-Statin/EGFL7 Antibody (2H6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: VE-Statin

EGFL7 (EGF-like domain-containing protein 7) regulates vascular tubulogenesis in vivo. During sprouting angiogenesis, groups of endothelial cells (ECs) migrate together in units called sprouts. EGFL7 regulates the proper spatial organization of ECs within each sprout and influences their collective movement. It inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Long Name

Vascular Endothelial Statin/EGF-like Domain, Multiple 7

Alternate Names

EGFL7, MEGF7, NOTCH4-like protein, VEStatin, ZNEU1

Entrez Gene IDs

51162 (Human)

Gene Symbol

EGFL7

OMIM

608582 (Human)

Additional VE-Statin Products

Product Documents for VE-Statin/EGFL7 Antibody (2H6)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VE-Statin/EGFL7 Antibody (2H6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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