VHLL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00391104-B01P-50ug

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
H00391104-B01P-50ug
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VHLL Antibodies »

Product Specifications

Immunogen

VHLL (ADR83480.1, 1 a.a. - 139 a.a.) full-length human protein. MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICNHSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVPSSNVNGQPVFANITLQCIP

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for VHLL Antibody

Western Blot: VHLL Antibody [H00391104-B01P-50ug]

Western Blot: VHLL Antibody [H00391104-B01P-50ug]

Western Blot: VHLL Antibody [H00391104-B01P-50ug] - Analysis of VHLL expression in transfected 293T cell line by VHLL MaxPab polyclonal antibody. Lane 1: VHLL transfected lysate(15.3 KDa). Lane 2: Non-transfected lysate.

Applications for VHLL Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: VHLL

Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that the selectivelyubiquitinates the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediateddegradation. Inactivation of VHL causes VHL disease and sporadic kidney cancer. This gene encodes a VHL homolog thatlacks one of two key domains necessary for VHL function. It binds HIF alpha but fails to recruit the E3 ubiquitinligase complex, and therefore functions as a dominant-negative VHL and a protector of HIF alpha. This gene isintronless and predominantly expressed in the placenta, and may contribute to the regulation of oxygen homeostasis andneovascularization during placenta development. (provided by RefSeq)

Alternate Names

VHL-like protein, VHLP, VLPVHL pseudogene, von Hippel-Lindau tumor suppressor-like, von Hippel-Lindau-like protein

Entrez Gene IDs

391104 (Human)

Gene Symbol

VHLL

UniProt

ADR83480.1 (Human)

Additional VHLL Products

Product Documents for VHLL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for VHLL Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.