Villin 1 Antibody (VIL1/2376) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08928JF646
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # VIL1/2376
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
A recombinant fragment (around aa 179-311) of human Villin 1 protein (exact sequence is proprietary) (Uniprot: P09327)
Localization
Cytoplasmic & Cell Surface
Specificity
Recognizes a protein of 95kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
Marker
GI-Mucosal & Urogenital Brush Border Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Villin 1 Antibody (VIL1/2376) [Janelia Fluor® 646]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Villin 1
Alternate Names
D2S1471, VIL, villin 1, villin-1
Gene Symbol
VIL1
Additional Villin 1 Products
Product Documents for Villin 1 Antibody (VIL1/2376) [Janelia Fluor® 646]
Product Specific Notices for Villin 1 Antibody (VIL1/2376) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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