VNN2 Antibody (3F8F8H6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06441

Novus Biologicals, part of Bio-Techne
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NBP3-06441-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Sandwich ELISA Capture

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3F8F8H6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all VNN2 Antibodies »

Product Summary for VNN2 Antibody (3F8F8H6)

Immunogen

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VNN2 (Accession#: NP_004656.2; Met 1-Ser 492).

Reactivity Notes

No cross-reactivity in ELISA with:

Human cell lysate (293 cell line)

Specificity

No cross-reactivity in ELISA with: Human cell lysate (293 cell line)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for VNN2 Antibody (3F8F8H6)

Flow Cytometry: VNN2 Antibody (3F8F8H6) [NBP3-06441]

Flow Cytometry: VNN2 Antibody (3F8F8H6) [NBP3-06441]

Flow Cytometry: VNN2 Antibody (3F8F8H6) [NBP3-06441] - Flow cytometric analysis of Human VNN2 expression on human whole blood monocytes (left panel) and granulocytes (right panel). Cells were stained with purified anti-Human VNN2, then a FITC-conjugated second step antibody. The histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes and granulocytes.

Applications for VNN2 Antibody (3F8F8H6)

Application
Recommended Usage

ELISA

1:1000-1:2000

Flow Cytometry

1:25-1:100

Sandwich ELISA Capture

1:250-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VNN2

VNN2 product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Alternate Names

EC 3.5.1, EC 3.5.1.92, FOAP-4, Glycosylphosphatidyl inositol-anchored protein GPI-80, GPI-80, GPI-80 variant protein 1, GPI-80 variant protein 2, GPI-80 variant protein 3, GPI-80 variant protein 4, pantetheinase, Protein FOAP-4, vanin 2, Vanin-2, Vannin 2, vascular non-inflammatory molecule 2

Gene Symbol

VNN2

Additional VNN2 Products

Product Documents for VNN2 Antibody (3F8F8H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VNN2 Antibody (3F8F8H6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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