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VNN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-79906

Novus Biologicals, part of Bio-Techne
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NBP1-79906

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Summary for VNN2 Antibody

Immunogen

The immunogen for this antibody is VNN2. Peptide sequence FRGFISRDGFNFTELFENAGNLTVCQKELCCHLSYRMLQKEENEVYVLGA. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for VNN2 Antibody

Western Blot: VNN2 Antibody [NBP1-79906]

Western Blot: VNN2 Antibody [NBP1-79906]

Western Blot: VNN2 Antibody [NBP1-79906] - Human Fetal kidney Lysate, concentration 1 ug/ml.

Applications for VNN2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VNN2

VNN2 product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Alternate Names

EC 3.5.1, EC 3.5.1.92, FOAP-4, Glycosylphosphatidyl inositol-anchored protein GPI-80, GPI-80, GPI-80 variant protein 1, GPI-80 variant protein 2, GPI-80 variant protein 3, GPI-80 variant protein 4, pantetheinase, Protein FOAP-4, vanin 2, Vanin-2, Vannin 2, vascular non-inflammatory molecule 2

Gene Symbol

VNN2

Additional VNN2 Products

Product Documents for VNN2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for VNN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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