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Von Willebrand Factor Antibody (CL1957)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34494

Novus Biologicals, part of Bio-Techne
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NBP2-34494
NBP2-34494-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL1957

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Von Willebrand Factor Antibody (CL1957)

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ARSNRVTVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTMVTLGNSFLHKLCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEKT

Epitope

MDEDGNEKRPGDVWT

Reactivity Notes

Expected identity based on immunogen sequence: Mouse (80%), Rat (80%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Von Willebrand Factor Antibody (CL1957)

Western Blot: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Western Blot: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Western Blot: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Lane 1: Marker [kDa]. Lane 2: Human spleen tissue lysate
Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human tonsil shows absence of immunoreactivity in lymphoid cells (negative control).
Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494]

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human rectum shows strong immunoreactivity in a blood vessel.

Applications for Von Willebrand Factor Antibody (CL1957)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Von Willebrand Factor

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Alternate Names

coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

Gene Symbol

VWF

UniProt

Additional Von Willebrand Factor Products

Product Documents for Von Willebrand Factor Antibody (CL1957)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Von Willebrand Factor Antibody (CL1957)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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