Von Willebrand Factor Antibody (rVWF/2480) [DyLight 550]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08944R
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry-Paraffin
Label
DyLight 550 (Excitation = 562 nm, Emission = 576 nm)
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # rVWF/2480
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Von Willebrand Factor Antibody (rVWF/2480) [DyLight 550]
Immunogen
Recombinant full-length human Von Willebrand Factor protein (Uniprot: P04275 )
Localization
Cytoplasm
Specificity
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Marker
Endothelial Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Von Willebrand Factor Antibody (rVWF/2480) [DyLight 550]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Von Willebrand Factor
Alternate Names
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Gene Symbol
VWF
Additional Von Willebrand Factor Products
Product Documents for Von Willebrand Factor Antibody (rVWF/2480) [DyLight 550]
Product Specific Notices for Von Willebrand Factor Antibody (rVWF/2480) [DyLight 550]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...