Von Willebrand Factor Antibody (VWF/1767) [DyLight 405]

Validated:

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Monoclonal Mouse IgG2b Kappa Clone # VWF/1767

Please see the vial label for concentration. If unlisted please contact technical services.

Recombinant fragment (around aa1815-1939) of human Von Willebrand Factor protein (exact sequence is proprietary) (Uniprot: P04275)

Cytoplasmic

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Endothelial Marker

Monoclonal

Mouse

IgG2b Kappa

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Protein A or G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.