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WBSCR22 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13520

Novus Biologicals, part of Bio-Techne
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NBP2-13520
NBP2-13520-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: ELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%). Human reactivity reported in scientific literature (PMID: 25851604).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for WBSCR22 Antibody

Immunocytochemistry/ Immunofluorescence: WBSCR22 Antibody [NBP2-13520]

Immunocytochemistry/ Immunofluorescence: WBSCR22 Antibody [NBP2-13520]

Immunocytochemistry/Immunofluorescence: WBSCR22 Antibody [NBP2-13520] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleus & nucleoli.
Immunohistochemistry-Paraffin: WBSCR22 Antibody [NBP2-13520]

Immunohistochemistry-Paraffin: WBSCR22 Antibody [NBP2-13520]

Immunohistochemistry-Paraffin: WBSCR22 Antibody [NBP2-13520] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for WBSCR22 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WBSCR22

WBSCR22 encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

Alternate Names

EC 2.1.1.-, FLJ44236, HASJ4442, HUSSY-3, MGC19709, MGC2022, MGC5140, PP3381, WBMT, Williams Beuren syndrome chromosome region 22, Williams Beuren syndrome chromosome region 22 protein, Williams-Beuren candidate region putative methyltransferase, Williams-Beuren syndrome chromosomal region 22 protein

Gene Symbol

WBSCR22

Additional WBSCR22 Products

Product Documents for WBSCR22 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for WBSCR22 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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