WDR46 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25230

Novus Biologicals, part of Bio-Techne
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NBP3-25230
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all WDR46 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein WDR46 using the following amino acid sequence: LSTRTLPHGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLEQPYLTHRLSGPVHGLQFCPFEDVLGVGHTGGITSMLV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for WDR46 Antibody

WDR46 Antibody Immunocytochemistry/Immunofluorescence: WDR46 Antibody [NBP3-25230]

Immunocytochemistry/Immunofluorescence: WDR46 Antibody [NBP3-25230]

Staining of human cell line MCF-7 shows localization to nucleoli.

Applications for WDR46 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WDR46

WDR46 was originally identified as BING-4, a protein encoded in a gene-rich region of the major histocompatibility complex (MHC). WDR46 has been found to be overexpressed in a subset of melanoma cell lines and is a cancer antigen recognized by lymphocytes. WDR46 bears six WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR46 has not been characterized.

Alternate Names

BING4FP221, C6orf11, chromosome 6 open reading frame 11, WD repeat domain 46, WD repeat-containing protein 46, WD repeat-containing protein BING4

Gene Symbol

WDR46

Additional WDR46 Products

Product Documents for WDR46 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for WDR46 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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