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WDR58 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31390

Novus Biologicals, part of Bio-Techne
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NBP2-31390
NBP2-31390-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TMDLETGTFTRVLRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRTAKEVQTIEVYKHEECSRPHNGRWIGCLATDSDWMVCGGGPALTLWHLRSSTPTTIFPIR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for WDR58 Antibody

Immunocytochemistry/ Immunofluorescence: WDR58 Antibody [NBP2-31390]

Immunocytochemistry/ Immunofluorescence: WDR58 Antibody [NBP2-31390]

Immunocytochemistry/Immunofluorescence: WDR58 Antibody [NBP2-31390] - Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: WDR58 Antibody [NBP2-31390]

Immunohistochemistry-Paraffin: WDR58 Antibody [NBP2-31390]

Immunohistochemistry-Paraffin: WDR58 Antibody [NBP2-31390] - Staining of human skin shows moderate nuclear positivity in keratinocytes.

Applications for WDR58 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WDR58

WDR58 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with splicedmRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Bindsto mRNA upstream of the exon-ju

Alternate Names

fSAP35WDR58, Functional spliceosome-associated protein 35, MGC2655, THO complex 6 homolog (Drosophila), THO complex subunit 6 homolog, WD repeat domain 58, WD repeat-containing protein 58

Gene Symbol

THOC6

UniProt

Additional WDR58 Products

Product Documents for WDR58 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for WDR58 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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