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WRCH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33639

Novus Biologicals, part of Bio-Techne
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NBP1-33639

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for WRCH1 Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human WRCH1. The exact sequence is proprietary.

Reactivity Notes

Rhesus Monkey (100%).

Localization

Cell membrane, Lipid-anchor, Cytoplasmic side, Golgi apparatus membrane, Lipid-anchor, Cell junction, focal adhesion, Cell projection, podosome

Specificity

Antibody reactive against peptide, detects immunogen. Further validation in progress.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for WRCH1 Antibody

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP1-33639]

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP1-33639]

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP1-33639] - Paraffin-embedded placenta. RHOU antibody dilution: :100.

Applications for WRCH1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: WRCH1

This protein is a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation.

Alternate Names

ARHU, CDC42L1GTP-binding protein-like 1, DJ646B12.2, fJ646B12.2, FLJ10616,2310026M05Rik, G28K, GTP-binding protein like 1, GTP-binding protein SB128, hG28K, ras homolog gene family, member U, ras-like gene family member U, Rho GTPase-like protein ARHU, rho-related GTP-binding protein RhoU, Ryu GTPase, Wnt-1 responsive Cdc42 homolog 1, WRCH-1, WRCH1CDC42-like GTPase 1

Entrez Gene IDs

58480 (Human)

Gene Symbol

RHOU

UniProt

Additional WRCH1 Products

Product Documents for WRCH1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for WRCH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.