WRCH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13230

Novus Biologicals, part of Bio-Techne
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NBP2-13230
NBP2-13230-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all WRCH1 Antibodies »

Product Summary for WRCH1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LREDVKVLIELDKCKEKPVPEEAA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for WRCH1 Antibody

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP2-13230]

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP2-13230]

Immunohistochemistry-Paraffin: WRCH1 Antibody [NBP2-13230] - Staining of human bronchus shows strong membranous and cytoplasmic positivity in respiratory epithelial cells.

Applications for WRCH1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: WRCH1

Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.; Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Cell junction > focal adhesion. Cell projection > podosome. Note: Localizes to podosomes in SRC-transformed cells.; Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.

Alternate Names

ARHU, CDC42L1GTP-binding protein-like 1, DJ646B12.2, fJ646B12.2, FLJ10616,2310026M05Rik, G28K, GTP-binding protein like 1, GTP-binding protein SB128, hG28K, ras homolog gene family, member U, ras-like gene family member U, Rho GTPase-like protein ARHU, rho-related GTP-binding protein RhoU, Ryu GTPase, Wnt-1 responsive Cdc42 homolog 1, WRCH-1, WRCH1CDC42-like GTPase 1

Gene Symbol

RHOU

Additional WRCH1 Products

Product Documents for WRCH1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for WRCH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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