XBP1 Antibody (S04-3E2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19927

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19927-100ul
NBP3-19927-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-3E2

Concentration

0.3 mg/ml

View all XBP1 Antibodies »

Product Summary for XBP1 Antibody (S04-3E2)

Immunogen

Recombinant protein of human XBP1 (Uniprot # P17861)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for XBP1 Antibody (S04-3E2)

Western Blot: XBP1 Antibody (S04-3E2) [NBP3-19927]

Western Blot: XBP1 Antibody (S04-3E2) [NBP3-19927]

Western Blot: XBP1 Antibody (S04-3E2) [NBP3-19927] - Western blot detection of XBP1 in HL-60, U2OS cell lysates using NBP3-19927 (1:1000 diluted). Predicted band size: 29kDa. Observed band size: 29kDa.

Applications for XBP1 Antibody (S04-3E2)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: XBP1

XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. The protein contains two domains commonly found in transcription factors that confer DNA binding and dimerization capability. This gene product was also separately identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. There is also a recent finding that the same agents that cause an ER stress response, the unfolded protein response, also increase transcription of this gene. This increase in transcription requires an ER stress response consensus binding element in the promoter.

Long Name

X-box Binding Protein 1

Alternate Names

HTF, TREB5, XBP2

Gene Symbol

XBP1

Additional XBP1 Products

Product Documents for XBP1 Antibody (S04-3E2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for XBP1 Antibody (S04-3E2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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