XRCC1 Antibody (33-2-5)

Novus Biologicals, part of Bio-Techne | Catalog # NB120-1838

Novus Biologicals, part of Bio-Techne
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NB120-1838-100ul
NB120-1838-500uL
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 33-2-5

Concentration

0.2 mg/ml

View all XRCC1 Antibodies »

Product Specifications

Immunogen

Recombinant human XRCC1 protein

Localization

Nuclear

Specificity

This is specific for XRCC1 (85 kDa).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for XRCC1 Antibody (33-2-5)

Western Blot: XRCC1 Antibody (33-2-5) [NB120-1838]

Western Blot: XRCC1 Antibody (33-2-5) [NB120-1838]

Western Blot: XRCC1 Antibody (33-2-5) [NB120-1838] - Analysis of LS174T Cells.
Immunohistochemistry-Paraffin: XRCC1 Antibody (33-2-5) [NB120-1838]

Immunohistochemistry-Paraffin: XRCC1 Antibody (33-2-5) [NB120-1838]

Immunohistochemistry-Paraffin: XRCC1 Antibody (33-2-5) [NB120-1838] - Rat testis stained with XRCC1 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of spermatocytes.
Immunohistochemistry: XRCC1 Antibody (33-2-5) [NB120-1838]

Immunohistochemistry: XRCC1 Antibody (33-2-5) [NB120-1838]

Immunohistochemistry: XRCC1 Antibody (33-2-5) [NB120-1838] - Formalin-fixed, paraffin-embedded human testis stained with XRCC1 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of spermatocytes.
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Applications for XRCC1 Antibody (33-2-5)

Application
Recommended Usage

Immunohistochemistry

1 - 2 ug/ml

Immunohistochemistry-Paraffin

1 - 2 ug/ml

Immunoprecipitation

2 ug/ml

Western Blot

1 - 2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: XRCC1

XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. In testis XRCC1 is expressed at high levels.

Alternate Names

DNA repair protein XRCC1, RCC, X-ray repair complementing defective repair in Chinese hamster cells 1, X-ray repair cross-complementing protein 1, X-ray-repair, complementing defective, repair in Chinese hamster

Entrez Gene IDs

7515 (Human); 84495 (Rat)

Gene Symbol

XRCC1

UniProt

P18887 (Human)

Additional XRCC1 Products

Product Documents for XRCC1 Antibody (33-2-5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for XRCC1 Antibody (33-2-5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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