Xrn1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89419

Novus Biologicals, part of Bio-Techne
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NBP1-89419
NBP1-89419-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Xrn1 Antibodies »

Product Summary for Xrn1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: NVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Xrn1 Antibody

Immunocytochemistry/ Immunofluorescence: Xrn1 Antibody [NBP1-89419]

Immunocytochemistry/ Immunofluorescence: Xrn1 Antibody [NBP1-89419]

Immunocytochemistry/Immunofluorescence: Xrn1 Antibody [NBP1-89419] - Staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: Xrn1 Antibody [NBP1-89419]

Immunohistochemistry-Paraffin: Xrn1 Antibody [NBP1-89419]

Immunohistochemistry-Paraffin: Xrn1 Antibody [NBP1-89419] - Staining of human urinary bladder shows weak cytoplasmic positivity in urothelial cells.

Applications for Xrn1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Xrn1

SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM]

Alternate Names

5'-3' exoribonuclease 1, DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, EC 3.1.11.-, SEP1FLJ41903, Strand-exchange protein 1 homolog

Gene Symbol

XRN1

Additional Xrn1 Products

Product Documents for Xrn1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Xrn1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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