ZBP1/DLM-1/DAI Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76854

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Cited:

Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ZBP1/DLM-1/DAI Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human ZBP1. The immunogen is located within the last 50 amino acids of ZBP1. Amino Acid Squence: TPSHSKLTPKLETMTLGN

Specificity

Multiple isoforms of ZBP1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ZBP1/DLM-1/DAI Antibody - BSA Free

Western Blot: ZBP1/DLM-1/DAI AntibodyBSA Free [NBP1-76854]

Western Blot: ZBP1/DLM-1/DAI AntibodyBSA Free [NBP1-76854]

Western Blot: ZBP1/DLM-1/DAI Antibody [NBP1-76854] - Mouse small intestine tissue lysate with Z DNA binding protein antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: ZBP1/DLM-1/DAI Antibody - BSA Free [NBP1-76854]

Immunocytochemistry/ Immunofluorescence: ZBP1/DLM-1/DAI Antibody - BSA Free [NBP1-76854]

Immunocytochemistry/Immunofluorescence: ZBP1/DLM-1/DAI Antibody [NBP1-76854] - Immunofluorescence of ZBP1 in Human Small Intestine tissue with ZBP1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: ZBP1/DLM-1/DAI Antibody - BSA Free [NBP1-76854]

Immunohistochemistry-Paraffin: ZBP1/DLM-1/DAI Antibody - BSA Free [NBP1-76854]

Immunohistochemistry-Paraffin: ZBP1/DLM-1/DAI Antibody [NBP1-76854] - Human small intestine tissue with Z DNA binding protein antibody at 2.5 ug/ml.

Applications for ZBP1/DLM-1/DAI Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZBP1/DLM-1/DAI

Z-DNA binding protein 1 (ZBP1) belongs to a family of proteins that contain the Zalpha domain which binds specifically to left-handed Z-DNA and Z-RNA. ZBP1 was initially identified as a novel gene that was up-regulated in activated macrophages in mice bearing ascites tumors, suggesting that is may play a role in processes such as host response in neoplasia. More recent reports indicate that the cytosolic ZBP1 has can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of ZBP1 to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and the serine/threonine kinase TBK1 (also known as NAK). Multiple isoforms of ZBP1 are known to exist.

Long Name

Zipcode-binding Protein 1

Alternate Names

DAI, DLM-1

Gene Symbol

ZBP1

UniProt

EAW75510 (Human)

Additional ZBP1/DLM-1/DAI Products

Product Documents for ZBP1/DLM-1/DAI Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ZBP1/DLM-1/DAI Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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