Zic2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55066

Novus Biologicals, part of Bio-Techne
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NBP2-55066
NBP2-55066-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Zic2 Antibodies »

Product Summary for Zic2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ELSLAAAQNGFVDSAAAHMGAFKLNPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Zic2 Antibody

Immunocytochemistry/ Immunofluorescence: Zic2 Antibody [NBP2-55066]

Immunocytochemistry/ Immunofluorescence: Zic2 Antibody [NBP2-55066]

Immunocytochemistry/Immunofluorescence: Zic2 Antibody [NBP2-55066] - Staining of human cell line U-2 OS shows localization to nuclear bodies.

Applications for Zic2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Zic2

ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.

Alternate Names

HPE5Zic family member 2 (odd-paired Drosophila homolog), Zic family member 2 (odd-paired homolog, Drosophila), Zinc finger protein of the cerebellum 2, zinc finger protein ZIC 2

Gene Symbol

ZIC2

Additional Zic2 Products

Product Documents for Zic2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Zic2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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