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Zic2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-86425

Novus Biologicals, part of Bio-Techne
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NBP2-86425-0.1ml

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for Zic2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human Zic2. Peptide sequence: EPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Zic2 Antibody

Western Blot: Zic2 Antibody [NBP2-86425]

Western Blot: Zic2 Antibody [NBP2-86425]

Western Blot: Zic2 Antibody [NBP2-86425] - Host: Rabbit. Target Name: ZIC2. Sample Tissue: Human HT1080 Whole Cell. Antibody Dilution: 1ug/ml
Immunohistochemistry: Zic2 Antibody [NBP2-86425]

Immunohistochemistry: Zic2 Antibody [NBP2-86425]

Immunohistochemistry: Zic2 Antibody [NBP2-86425] - Human Skin
Western Blot: Zic2 Antibody [NBP2-86425]

Western Blot: Zic2 Antibody [NBP2-86425]

Western Blot: Zic2 Antibody [NBP2-86425] - WB Suggested Anti-ZIC2 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate

Applications for Zic2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Zic2

ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.

Alternate Names

HPE5Zic family member 2 (odd-paired Drosophila homolog), Zic family member 2 (odd-paired homolog, Drosophila), Zinc finger protein of the cerebellum 2, zinc finger protein ZIC 2

Gene Symbol

ZIC2

Additional Zic2 Products

Product Documents for Zic2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Zic2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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