Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ZMYM1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM1 . The immunogen is located within amino acids 990 - 1040 of ZMYM1. Amino Acid Squence: WNEPLNETTAKHVQEFY

Specificity

At least two isoforms of ZMYM1 are known to exist; this antibody will detect only the shorter isoform. ZMYM1 antibody is predicted to not cross-react with other ZMYM protein family members.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZMYM1 Antibody - BSA Free

Western Blot: ZMYM1 AntibodyBSA Free [NBP1-76523]

Western Blot: ZMYM1 AntibodyBSA Free [NBP1-76523]

Western Blot: ZMYM1 Antibody [NBP1-76523] - Rat lung tissue lysate with ZMYM1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
ZMYM1 Antibody - BSA Free

Immunohistochemistry: ZMYM1 Antibody - BSA Free [NBP1-76523] -

Immunohistochemistry: ZMYM1 Antibody - BSA Free [NBP1-76523] - Immunohistochemistry of ZMYM1 in rat lung tissue with ZMYM1 antibody at 5 ug/mL.

Applications for ZMYM1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZMYM1

Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.

Alternate Names

FLJ23151, zinc finger, MYM domain containing 1, zinc finger, MYM-type 1

Gene Symbol

ZMYM1

UniProt

NP_079048 (Human)

Additional ZMYM1 Products

Product Documents for ZMYM1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ZMYM1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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