ZNF198 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-95284

Novus Biologicals, part of Bio-Techne
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NBP2-95284-100ul
NBP2-95284-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ZNF198 Antibodies »

Product Summary for ZNF198 Antibody

Immunogen

Produced in rabbits immunized with A synthetic peptide corresponding to the C-terminus of the human ZNF198.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ZNF198 Antibody

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284] - Immunochemical staining of human ZNF198 in human breast carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284]

Immunohistochemistry-Paraffin: ZNF198 Antibody [NBP2-95284] - Immunochemical staining of human ZNF198 in human brain with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Applications for ZNF198 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000-1:4000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZNF198

Official Gene Symbol: ZMYM2 Gen Bank Accession Number: NP_932072 Gene ID: 7750 (Human) Gene Map Locus: 13q11-q12 (Human) ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.

Alternate Names

FIMRAMPSCLL, Fused in myeloproliferative disorders protein, MYM, Rearranged in atypical myeloproliferative disorder protein, Zinc finger protein 198rearranged in an atypical myeloproliferative disorder, zinc finger, MYM-type 2, ZNF198zinc finger MYM-type protein 2

Gene Symbol

ZMYM2

Additional ZNF198 Products

Product Documents for ZNF198 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ZNF198 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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