ZNF198 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-29228

Novus Biologicals, part of Bio-Techne
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NBP3-29228
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ZNF198 Antibodies »

Product Specifications

Immunogen

Between 1327 and 1377

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for ZNF198 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-buffered Saline 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ZNF198

Official Gene Symbol: ZMYM2 Gen Bank Accession Number: NP_932072 Gene ID: 7750 (Human) Gene Map Locus: 13q11-q12 (Human) ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.

Alternate Names

FIMRAMPSCLL, Fused in myeloproliferative disorders protein, MYM, Rearranged in atypical myeloproliferative disorder protein, Zinc finger protein 198rearranged in an atypical myeloproliferative disorder, zinc finger, MYM-type 2, ZNF198zinc finger MYM-type protein 2

Gene Symbol

ZMYM2

Additional ZNF198 Products

Product Documents for ZNF198 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ZNF198 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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