Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ZNF536 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ZNF536. The immunogen is located within amino acids 30 - 80 of ZNF536. Amino Acid Squence: PELHPRPNPEEKPPAS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZNF536 Antibody - BSA Free

Western Blot: ZNF536 AntibodyBSA Free [NBP1-77092]

Western Blot: ZNF536 AntibodyBSA Free [NBP1-77092]

Western Blot: ZNF536 Antibody [NBP1-77092] - Human brain tissue lysate with ZNF536 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: ZNF536 Antibody - BSA Free [NBP1-77092]

Immunocytochemistry/ Immunofluorescence: ZNF536 Antibody - BSA Free [NBP1-77092]

Immunocytochemistry/Immunofluorescence: ZNF536 Antibody [NBP1-77092] - Immunofluorescence of ZNF536 in human brain tissue with ZNF536 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: ZNF536 Antibody - BSA Free [NBP1-77092]

Immunohistochemistry-Paraffin: ZNF536 Antibody - BSA Free [NBP1-77092]

Immunohistochemistry-Paraffin: ZNF536 Antibody [NBP1-77092] - Human brain tissue with ZNF536 antibody at 5 ug/mL.
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Applications for ZNF536 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZNF536

ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.

Alternate Names

KIAA0390, zinc finger protein 536

Gene Symbol

ZNF536

UniProt

NP_055532 (Human)

Additional ZNF536 Products

Product Documents for ZNF536 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ZNF536 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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