Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all ZNRF2 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human zinc and ring finger 2 using the numbering given in entry NP_667339.1 (GeneID 223082).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZNRF2 Antibody

Immunoprecipitation: ZNRF2 Antibody [NBP1-28697]

Immunoprecipitation: ZNRF2 Antibody [NBP1-28697]

Immunoprecipitation: ZNRF2 Antibody [NBP1-28697] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ZNRF2 antibody NBP1-28697 used for IP at 10 ug/mg lysate. ZNRF2 was also immunoprecipitated by rabbit anti-ZNRF2 antibody NBP1-28715, which recognizes a downstream epitope. For blotting immunoprecipitated ZNRF2, NBP1-28715 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Applications for ZNRF2 Antibody

Application
Recommended Usage

Immunoprecipitation

10 ug/mg lysate
Application Notes
It is not recommended for western analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ZNRF2

Zinc- and RING- finger 2 (ZNRF2) is suggested to play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Alternate Names

EC 6.3.2.-, Protein Ells2, RING finger protein 202, RNF202E3 ubiquitin-protein ligase ZNRF2, zinc and ring finger 2, zinc finger/RING finger 2, Zinc/RING finger protein 2

Entrez Gene IDs

223082 (Human)

Gene Symbol

ZNRF2

UniProt

NP_667339.1 (Human)

Additional ZNRF2 Products

Product Documents for ZNRF2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ZNRF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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