ZP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86103

Novus Biologicals, part of Bio-Techne
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NBP1-86103
NBP1-86103-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ZP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PNCTYILDPEKLTLRATYDNCTRRVHGGHQMTIRVMNNSAALRHGAVMYQFFCPAMQVEETQGLSASTICQKDFMSFSLPRVFSGLADDSKGTKVQMGWSIEVGDGARAKTLTLPEAMKEGFSLLIDNHRMTFHVPFNATGVT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZP2 Antibody

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103] - Staining of human endometrium shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103]

Immunohistochemistry-Paraffin: ZP2 Antibody [NBP1-86103] - Staining of human prostate shows no positivity in glandular cells as expected.
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Applications for ZP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZP2

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq]

Long Name

Zona Pellucida Glycoprotein 2 (Sperm Receptor)

Alternate Names

Zona Pellucida Protein A, Zp-2, ZPA

Entrez Gene IDs

7783 (Human)

Gene Symbol

ZP2

UniProt

Q05996 (Human)

Additional ZP2 Products

Product Documents for ZP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ZP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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