ChABC Antibody Pair

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97919

Novus Biologicals, part of Bio-Techne
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NBP1-97919
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Key Product Details

Reactivity

Non-species specific

View all ChABC ELISA Kits »

Product Specifications

Conjugate

Unconjugated

Application Notes

ELISA data: Capture Antibody ChABC/6A12 [NBP1-96142] was bound to a 96-well ELISA plate and serial dilutions of ChABC were added in physiological buffer. Bound ChABC was labeled using Detection Antibody biotinylated ChABC/1E10 [NBP1-96141B]. Bound Detection Antibody was labeled with avidin-HRP and the assay developed with chromagen OPDA/ H2O2.

Scientific Data Images for ChABC Antibody Pair

ELISA: ChABC Antibody Pair [NBP1-97919]

ELISA: ChABC Antibody Pair [NBP1-97919]

ELISA: ChABC Antibody Pair [NBP1-97919] - Standard curve for serial dilutions of ChABC. See Notes for additional information.

Preparation and Storage

Formulation

NBP1-96141B: PBS with No Preservative
NBP1-96142: Tris-glycine, 150mM NaCl pH 7.5 and 0.05% Sodium Azide

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ChABC

ChABC (Chondroitinase ABC) is a bacterial enzyme that has been used for decades, mostly for biochemical characterization of chondroitin sulfate proteoglycans (CSPG). This enzyme degrades the sugar chains attached to the proteoglycan core protein. More recently, ChABC has been used to therapeutically degrade and inactivate CSPG in vivo. CSPGs are involved in a variety of biological processes and play a major inhibitory role in regeneration in the nervous system. For instance, CSPGs have been implicated in preventing regeneration after spinal cord injury. Injection of ChABC at the site of spinal cord injury has improved recovery in numerous animal models. ChABC antibodies serve as tools to help determine the ChABC distribution and content in tissues.

Alternate Names

Chondroitinase ABC

Additional ChABC Products

Product Documents for ChABC Antibody Pair

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ChABC Antibody Pair

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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