Complement Component C5/C5a Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79676

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-79676-15Plates
NBP2-79676-5Plates
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

23.44-1500 pg/ml (example only; lot dependent)

Sensitivity

23.44 pg/ml (example only; lot dependent)

Reactivity

Human

View all Complement Component C5/C5a ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human Complement Component C5/C5a.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for Complement Component C5/C5a Antibody Pair [HRP]

Sandwich ELISA: Complement Component C5/C5a Antibody Pair [HRP] [NBP2-79676] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for Complement Component C5/C5a Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP3-06192)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Complement Component C5/C5a

Human complement component C5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 alpha-chain. Human C5a has four alpha-helices plus three intrachain disulfide bonds that create a triple loop structure. In serum, proteolytic processing removes the C-terminal arginine, creating a low activity C5a desArg74 molecule. Human C5a is 60% and 54% aa identical to mouse and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a non-signaling GPCR termed C5L2. Activation of CD88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.

Alternate Names

C5

Gene Symbol

C5

Additional Complement Component C5/C5a Products

Product Documents for Complement Component C5/C5a Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Complement Component C5/C5a Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.