Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence)

Name: Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence)
Brand: Novus Biologicals
SKU: NBP2-67941

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-67941

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Product Specifications
Precision
Recovery
Linearity
Scientific Data
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

18.75 pg/mL

Assay Range

31.25-2000 pg/mL

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Product Specifications

Assay Type

Sandwich-CLIA

Kit Type

ELISA Kit (Chemiluminescence)

Reactivity

Rat

Specificity

This kit recognizes Rat DRD4 in samples. No significant cross-reactivity or interference between Rat DRD4 and analogues was observed.

Precision

Intra-Assay Precision (Precision within an assay) CV% < 8.83%

Inter-Assay Precision (Precision between assays) CV% < 11.14%

Recovery for Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence)

Recovery

87-114%

Linearity

Scientific Data Images for Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence)

ELISA: Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence) [NBP2-67941] -

ELISA: Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence) [NBP2-67941] - Standard Curve Reference

Kit Contents for Rat Dopamine Receptor D4 ELISA Kit (Chemiluminescence)

Biotinylated Detection Ab Diluent
Concentrated Biotinylated Detection Ab (100x)
Concentrated HRP Conjugate (100x)
Concentrated Wash Buffer (25x)
HRP Conjugate Diluent
Micro CLIA Plate (Dismountable)
Plate Sealer
Product Manual
Reference Standard
Sample Diluent
Substrate Reagent A
Substrate Reagent B

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Dopamine Receptor D4

DRD4, a Dopamine Receptor, has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. DRD4 knock-out mice are anatomically normal but display altered locomotion and sensitivity to drugs such as clozapine, cocaine, and others. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor; at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome); however, considerable debates exist regarding the validity and significance of such associations. DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens. ESTs have been isolated from a kidney library.

Long Name

D(4) dopamine receptor

Alternate Names

DRD4

Gene Symbol