Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80378

Novus Biologicals, part of Bio-Techne
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Key Product Details

Sample Type & Volume Required Per Well

Serum (100 ul)

Sensitivity

28 pg/ml

Assay Range

39-2500 pg/ml (example only; lot dependent)

View all ErbB3/Her3 ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Conjugate

HRP

Reactivity

Mouse

Specificity

Recognizes both recombinant and natural Mouse ErbB3/Her3.

Precision

Intra-Assay Precision (Precision within an assay) CV% < 3.3

Inter-Assay Precision (Precision between assays) CV% < 6.3 %

Recovery for Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

Recovery

88%-90%

Scientific Data Images for Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

ELISA: Mouse ErbB3/Her3 ELISA Kit (Colorimetric) [NBP2-80378]

ELISA: Mouse ErbB3/Her3 ELISA Kit (Colorimetric) [NBP2-80378]

ELISA: Mouse ErbB3/Her3 ELISA Kit (Colorimetric) [NBP2-80378] - Example standard curve for Mouse ErbB3/Her3 ELISA Kit (Colorimetric). These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Kit Contents for Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

  • 1. 96 well microplate coated with Capture Antibody
  • 2. Detection Antibody conjugated to HRP
  • 3. Standards
  • 4. Wash Buffer Concentrate
  • 5. Dilution Buffer Concentrate
  • 6. Color Reagent A
  • 7. Color Reagent B
  • 8. Stop Solution

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage is content dependent.

Background: ErbB3/Her3

The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.

Long Name

Receptor Tyrosine Protein Kinase ErbB3

Alternate Names

HER3

Gene Symbol

ERBB3

Additional ErbB3/Her3 Products

Product Documents for Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mouse ErbB3/Her3 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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