IFN-gamma R1/CD119 Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79602

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-79602-15Plates
NBP2-79602-5Plates
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Assay Type

Sandwich ELISA

Assay Range

15.625-1000 pg/ml (example only; lot dependent)

Sensitivity

15.625 pg/ml (example only; lot dependent)

Reactivity

Mouse

View all IFN-gamma R1/CD119 ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Mouse IFN-gamma R1/CD119.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for IFN-gamma R1/CD119 Antibody Pair [HRP]

Sandwich ELISA: IFN-gamma R1/CD119 Antibody Pair [HRP] [NBP2-79602] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for IFN-gamma R1/CD119 Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-90685)
  • Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-90686)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IFN-gamma R1/CD119

IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains.

Long Name

Interferon gamma Receptor 1

Alternate Names

CD119, IFN-gR1, IFNgammaR1, IFNGR1

Gene Symbol

IFNGR1

Additional IFN-gamma R1/CD119 Products

Product Documents for IFN-gamma R1/CD119 Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IFN-gamma R1/CD119 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.