Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-06817

Novus Biologicals, part of Bio-Techne
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NBP3-06817
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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma, cell supernatant, and other biological fluids (100 ul)

Sensitivity

46.88 pg/mL

Assay Range

78.13 - 5000 pg/mL

View all IFN-gamma R1/CD119 ELISA Kits »

Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Mouse

Specificity

This kit recognizes Mouse IFN-gamma R1/CD119 in samples. No significant cross-reactivity or interference between Mouse IFN-gamma R1/CD119 and analogues was observed.

Precision

Intra-Assay Precision (Precision within an assay) 5.36

Inter-Assay Precision (Precision between assays) 5.84

Recovery for Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

Recovery

87 - 110 %

Linearity

Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

Scientific Data Images for Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

ELISA: Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric) [NBP3-06817] -

ELISA: Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric) [NBP3-06817] - Standard Curve Reference

Kit Contents for Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IFN-gamma R1/CD119

IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains.

Long Name

Interferon gamma Receptor 1

Alternate Names

CD119, IFN-gR1, IFNgammaR1, IFNGR1

Gene Symbol

IFNGR1

Additional IFN-gamma R1/CD119 Products

Product Documents for Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mouse IFN-gamma R1/CD119 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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