IL-1 RI Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79665

Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

46.88-3000 pg/ml (example only; lot dependent)

Sensitivity

46.88 pg/ml (example only; lot dependent)

Reactivity

Human

View all IL-1 RI ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human IL-1 RI.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for IL-1 RI Antibody Pair [HRP]

Sandwich ELISA: IL-1 RI Antibody Pair [HRP] [NBP2-79665] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for IL-1 RI Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Rabbit Polyclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL-1 RI

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Long Name

Interleukin 1 Receptor I

Alternate Names

CD121a, IL-1RI, IL1R1, IL1RI

Gene Symbol

IL1R1

Additional IL-1 RI Products

Product Documents for IL-1 RI Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-1 RI Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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