IL-21 ELISA Development Kit

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11754

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-11754
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Assay Range

7 - 700 pg/mL

Sample Type

Serum, plasma, cell culture supernatants (100 uL)

Reactivity

Non-human Primate

View all IL-21 ELISA Kits »

Product Specifications

Sample Volume Required

100 uL

Conjugate

Unconjugated

Scientific Data Images for IL-21 ELISA Development Kit

ELISA: IL-21 ELISA Development Kit [NBP3-11754]

ELISA: IL-21 ELISA Development Kit [NBP3-11754]

ELISA: IL-21 ELISA Development Kit [NBP3-11754] - Standard curve reference

Kit Contents for IL-21 ELISA Development Kit

  • Biotinylated detection mAb (MT21.3m)
  • Capture mAb (MT216G)
  • Recombinant human IL-21 ELISA standard
  • Standard reconstitution buffer
  • Streptavidin-HRP

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: IL-21

IL-21 (Interleukin-21) is member of the family of cytokines that utilize the common gamma chain as a receptor subunit. This subunit is also a component of the receptors for IL-2, IL-4, IL-7, IL-9, and IL-15. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex of the common gamma chain and the IL-21-specific IL-21 R. IL-21 supports Tfh cell development, immunoglobulin affinity maturation, plasma cell differentiation, B cell memory responses, and the migration of dendritic cells to draining lymph nodes. It costimulates the activation, proliferation, and survival of CD8+ T cells and NKT cells and promotes Th17 cell polarization. It blocks the generation of regulatory T cells and their suppressive effects on CD4+ T cells. In addition, IL-21 suppresses cutaneous hypersensitivity reactions by limiting allergen-specific IgE production and mast cell degranulation.

Long Name

Interleukin 21

Alternate Names

CVID11, IL21, Za11

Gene Symbol

IL21

Additional IL-21 Products

Product Documents for IL-21 ELISA Development Kit

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-21 ELISA Development Kit

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.