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Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18775

Novus Biologicals, part of Bio-Techne
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NBP3-18775

Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

9.38 pg/mL

Assay Range

15.63-1000 pg/mL

Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Specificity

This kit recognizes Human Neuregulin-1/NRG1 in samples. No significant cross-reactivity or interference between Human Neuregulin-1/NRG1 and analogues was observed.

Precision

Intra-Assay Precision (Precision within an assay) %CV < 5.62

Inter-Assay Precision (Precision between assays) %CV < 6.01

Recovery for Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

Recovery

85-110%

Linearity

Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

Scientific Data Images for Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

ELISA: Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric) [NBP3-18775] -

ELISA: Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric) [NBP3-18775] - Standard Curve Reference

Kit Contents for Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Neuregulin-1/NRG1

Neuregulin 1 (NRG1, isoform HRG-beta2) belongs to the neuregulin/heregulin cytokine family consisting of variants of the four genes NRG1, NRG2, NRG3 and NRG4. More than 15 transmembrane and secreted protein isoforms exist for NRG1, they are generated by alternative promoter usage and mRNA splicing. The different isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. The EGF-like domain interacts with ErbB3 and ErbB4 tyrosine kinase receptors, resulting in tyrosine phosphorylation and NRG1 signaling. NRG proteins show distinct spatial and temporal expression patterns. These proteins are important for the development of the nervous system and the heart and in the regulation of neurotransmission.

Alternate Names

Heregulin-1, HGL, HRG1-alpha, HRG1-beta 1, Neuregulin1, NRG1

Gene Symbol

NRG1

Additional Neuregulin-1/NRG1 Products

Product Documents for Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Human Neuregulin-1/NRG1 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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