Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76761

Novus Biologicals, part of Bio-Techne
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NBP2-76761
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Key Product Details

Sample Type & Volume Required Per Well

Serum, plasma and other biological fluids (100 uL)

Sensitivity

0.094ng/mL

Assay Range

0.156 - 10ng/mL

View all Neuregulin-3/NRG3 ELISA Kits »

Product Specifications

Assay Type

Sandwich-ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Precision

Intra-Assay Precision (Precision within an assay) CV% < 4.51

Inter-Assay Precision (Precision between assays) CV% < 5.41

Recovery for Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

Recovery

87-105%

Linearity

Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

Scientific Data Images for Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

ELISA: Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric) [NBP2-76761] -

ELISA: Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric) [NBP2-76761] - Standard Curve Reference

Kit Contents for Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

  • Biotinylated Detection Ab Diluent
  • Concentrated Biotinylated Detection Ab (100x)
  • Concentrated HRP Conjugate (100x)
  • Concentrated Wash Buffer (25x)
  • HRP Conjugate Diluent
  • Micro ELISA Plate (Dismountable)
  • Plate Sealer
  • Product Manual
  • Reference Standard
  • Sample Diluent
  • Stop Solution
  • Substrate Reagent

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Neuregulin-3/NRG3

NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization.

Alternate Names

Neuregulin3, NRG3

Gene Symbol

NRG3

Additional Neuregulin-3/NRG3 Products

Product Documents for Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Human Neuregulin-3/NRG3 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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