Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

Name: Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)
Brand: Novus Biologicals
SKU: NBP3-14637

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14637

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Product Specifications
Precision
Recovery
Scientific Data
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Sample Type & Volume Required Per Well

Serum, Cell lysates, Cell culture supernatant (100 ul)

Sensitivity

6 pg/ml

Assay Range

31.25-1000 pg/ml

View all TRAIL R2/TNFRSF10B ELISA Kits »

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Human

Specificity

Specific for human TRAILR2/TNFRSF10B. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R3, TRAIL R4, CD178 and Granzyme B..

Description

Incubation: 2 hours 30 minutes

Precision

Intra-Assay Precision (Precision within an assay) CV% < 3.2

Inter-Assay Precision (Precision between assays) CV% < 7.4

Recovery for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

Recovery

83 to 124%

Scientific Data Images for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

ELISA: Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric) [NBP3-14637]

ELISA: Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric) [NBP3-14637] - Example of Human TRAILR2/TNFRSF10B Standard Curve.

Kit Contents for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

Biotinylated secondary antibody
Buffers
Controls (where applicable)
Detailed procedure.
Pre-coated strip plates
Standards
Stop reagents
Streptavidin-HRP
TMB

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: TRAIL R2/TNFRSF10B

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Long Name

TRAIL Receptor 2

Alternate Names

CD262, DR5, TNFRSF10B, TRAILR2

Gene Symbol

TNFRSF10B

Additional TRAIL R2/TNFRSF10B Products

Product Documents for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

Product Datasheets

Download Product Datasheets

Protocols & Manuals

Download Manual - NBP3-14637

COA

SDS

Download SDS

Product Specific Notices for Human TRAILR2/TNFRSF10B ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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