IPG-4 AM

Name: IPG-4 AM
Brand: Tocris Bioscience
SKU: 7871

Tocris Bioscience, part of Bio-Techne | Catalog # 7871

COA / SDS

Fluorescent potassium ion (K+) indicator, membrane permeable

Key Product Details

Description:	Fluorescent potassium ion (K⁺) indicator, membrane permeable
Chemical Name:	Acetyloxymethyl 3-[3-(acetyloxymethoxy)-7-[3-(acetyloxymethoxy)-3-oxopropyl]-4,5-dichloro-9-[4-(5,17-dimethyl-8,14,24,27,32,35-hexaoxa-1,11,21-triazatetracyclo[19.8.8.02,7.015,20]heptatriaconta-2(7),3,5,15(20),16,18-hexaen-11-yl)-3-(2-methoxyethoxy)phenyl]-6-oxoxanthen-2-yl]propanoate
Purity:	≥90% (HPLC)
Molecular Weight:	1333.27

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Technical Data
Citations

Biological Activity for IPG-4 AM

IPG-4 AM is a membrane-permeable fluorescent potassium ion (K⁺) indicator. It binds to potassium (K_d = 7 mM). Excitation and emission maxima (λ) are 525 and 545 nm, respectively. It has 100:1 selectivity for K⁺ over Na⁺ ions. It can be used to detect in real time changes in intracellular K⁺. Also used to monitor extracellular K⁺ changes in vivo.

It is recommended to prepare stock solutions in DMSO.

Optical Data for IPG-4 AM

λ_abs	525 nm
λ_em	545 nm
Cell Permeable	Yes
Application	Confocal microscopy, Flow cytometry

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Technical Data for IPG-4 AM

M. Wt	1333.27
Formula	C₆₇H₇₉Cl₂N₃O₂₁
Storage	Store at -20°C
Purity	≥90% (HPLC)
PubChem ID	163342041
InChi Key	ORCBRKCLNTYBFH-UHFFFAOYSA-N
Smiles	O=C(C)OCOC(CCC1=CC2=C(C3=CC(OCCOC)=C(N(CCOC4=C5C=CC(C)=C4)CCOC6=C(N7CCOCCOCCN5CCOCCOCC7)C=CC(C)=C6)C=C3)C8=C(C(Cl)=C(C(CCC(OCOC(C)=O)=O)=C8)OCOC(C)=O)OC2=C(C1=O)Cl)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for IPG-4 AM

References are publications that support the biological activity of the product.

Hanalioglu Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. J.Headache Pain 2022 PMID: 35986251
Kikuchi Electrochemical potential enables dormant spores to integrate environmental signals. Science 2022 PMID: 36201591
Humphries Species-independent attraction to biofilms through electrical signaling. Cell 2017 PMID: 28086091
Rana Calibration and characterization of intracellular Asante Potassium Green probes, APG-2 and APG-4. Anal.Biochem. 2019 PMID: 30503709